If the Eagles win in Seattle, it would be the third straight home for loss for Seahawks, who were once invincible at CenturyLink Field. A rash of injuries has made them vulnerable.

The key for the Bengals will be running the ball — which Green Bay did with success — to control the clock and keep Pittsburgh’s “Killer Bs” on the sideline. Bengals rookie Joe Mixon is coming off his first career 100-yard game and has three touchdowns over the last four games.

Ohtani has inspired strong reactions ever since the world became aware of the Japanese star’s formidable talent as both a pitcher and a hitter. Now that the Angels have landed such a coveted prize, they can’t wait to see who else he can knock over.

“You just feel good and feel proud for two young guys to be able to go through what they did through their rookie year and be able to come back their second year and have the accomplishments.”

Q: In the latest Pro Bowl fan voting, you’re No. 6 in the league, how do you feel about that?

Gurley: “I don’t know. I really try not to think about it that much. Obviously, I was blessed to be in it my rookie year and last year I wasn’t in it. Definitely excited, but my main focus is, I don’t even want to play in it. I want to be able to still be playing and competing for a Super Bowl.

Reason for optimism: Star running back Ezekiel Elliott will be returning from his six-game domestic violence suspension in Week 16 against Seattle. Outside linebacker Sean Lee, who is the defense’s lynchpin, is back Sunday against the Giants after missing the past three games with a strained hamstring.